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ACSS2
Activates acetate so that it can be used for lipid synthesis or for energy generation. Belongs to the ATP-dependent AMP-binding enzyme family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - pyruvate; EC 6.2.1.1; Ligase |
| Chromosomal Location of Human Ortholog: 2|2 H1 |
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Cellular Component:
cytoplasm; cytosol; intracellular membrane-bounded organelle; nucleoplasm
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Molecular Function:
acetate-CoA ligase activity; AMP binding; ATP binding; catalytic activity; ligase activity; nucleotide binding
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Biological Process:
acetate biosynthetic process; acetyl-CoA biosynthetic process; acetyl-CoA biosynthetic process from acetate; lipid biosynthetic process; propionate biosynthetic process
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Reference #:
Q9QXG4
(UniProtKB)
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Alt. Names/Synonyms: 1110017C11Rik; ACAS; Acas1; Acas2; AceCS; Acecs1; Acetate--CoA ligase; Acetyl-CoA synthetase; acetyl-CoA synthetase 1; acetyl-Coenzyme A synthetase 1 (AMP forming); acetyl-Coenzyme A synthetase 2 (ADP forming); acetyl-Coenzyme A synthetase 2 (AMP forming); Acetyl-coenzyme A synthetase, cytoplasmic; ACS; Acs1; ACSA; Acss2; Acyl-activating enzyme; Acyl-CoA synthetase short-chain family member 2; OTTMUSP00000017177
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Gene Symbols: Acss2
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Molecular weight:
78,862 Da
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Basal Isoelectric point:
6.19
Predict pI for various phosphorylation states
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Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®
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