RASA2 Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Ras
Chromosomal Location of mouse Ortholog: 9|9 E3.3
Cellular Component:  membrane; plasma membrane
Molecular Function:  GTPase activator activity; metal ion binding; phospholipid binding
Biological Process:  intracellular signal transduction; negative regulation of Ras protein signal transduction; regulation of GTPase activity
Reference #:  P58069 (UniProtKB)
Alt. Names/Synonyms: 5430433H21Rik; AA517451; AU023900; GAP; GAP1m; OTTMUSP00000022558; Ras GTPase-activating protein 2; RAS p21 protein activator 2; Rasa2
Gene Symbols: Rasa2
Molecular weight: 96,401 Da
Basal Isoelectric point: 7.67  Predict pI for various phosphorylation states
CST Pathways:  B Cell Receptor Signaling  |  GPCR Signaling to MAPKs  |  T Cell Receptor Signaling
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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RASA2

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein