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RASA2
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: GAP; GAP, Ras |
| Chromosomal Location of human Ortholog: 3q23 |
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Cellular Component:
cytosol; perinuclear region of cytoplasm
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Molecular Function:
GTPase activator activity; metal ion binding; phospholipid binding
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Biological Process:
intracellular signal transduction; negative regulation of Ras protein signal transduction; regulation of GTPase activity; signal transduction
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Reference #:
Q15283
(UniProtKB)
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Alt. Names/Synonyms: GAP1M; GTPase-activating protein 1m; GTPase-activating protein of RAS; Ras GTPase-activating protein 2; RAS p21 protein activator 2; RASA2; RASGAP
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Gene Symbols: RASA2
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Molecular weight:
96,614 Da
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Basal Isoelectric point:
6.84
Predict pI for various phosphorylation states
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CST Pathways:
B Cell Receptor Signaling
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GPCR Signaling to MAPKs
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T Cell Receptor Signaling
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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