WDR75
Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Note: This description may include information from UniProtKB.
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Protein type: Nucleolus; Unknown function |
Chromosomal Location of human Ortholog: 2q32.2 |
Cellular Component:
nucleolus; nucleoplasm; small-subunit processome
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Molecular Function:
RNA binding
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Biological Process:
positive regulation of rRNA processing; positive regulation of transcription by RNA polymerase I; ribosomal small subunit biogenesis; rRNA processing
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Reference #:
Q8IWA0
(UniProtKB)
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Alt. Names/Synonyms: DKFZp781N1244; FLJ12519; NET16; U3 small nucleolar RNA-associated protein 17 homolog; UTP17; UTP17, small subunit (SSU) processome component, homolog; WD repeat domain 75; WD repeat-containing protein 75; WDR75
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Gene Symbols: WDR75
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Molecular weight:
94,499 Da
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Basal Isoelectric point:
5.65
Predict pI for various phosphorylation states
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