VEZATIN Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. Required for morphogenesis of the preimplantation embryo, and for the implantation process. (Microbial infection) In case of Listeria infection, promotes bacterial internalization by participating in myosin VIIa recruitment to the entry site. Belongs to the vezatin family. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 12q22
Cellular Component:  acrosomal vesicle; adherens junction; cytosol; integral component of membrane; nucleoplasm; stereocilia ankle link complex; stereocilium membrane
Molecular Function:  myosin binding
Biological Process:  cell-cell adhesion
Reference #:  Q9HBM0 (UniProtKB)
Alt. Names/Synonyms: DKFZp761C241; transmembrane protein vezatin; VEZA; Vezatin; vezatin, adherens junctions transmembrane protein; VEZT
Gene Symbols: VEZT
Molecular weight: 88,665 Da
Basal Isoelectric point: 5.11  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene