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ATP6V1C2
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase C subunit family. Kidney and placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.6.3.14; Energy Metabolism - oxidative phosphorylation; Hydrolase |
| Chromosomal Location of mouse Ortholog: 12|12 A1.1 |
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Cellular Component:
proton-transporting V-type ATPase, V1 domain; vacuolar proton-transporting V-type ATPase, V1 domain
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Molecular Function:
identical protein binding; proton transmembrane transporter activity; proton-transporting ATPase activity, rotational mechanism
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Biological Process:
monoatomic ion transport; positive regulation of Wnt signaling pathway; proton transmembrane transport
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Reference #:
Q99L60
(UniProtKB)
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Alt. Names/Synonyms: 1110038G14Rik; Atp6c2; Atp6v1c2; ATPase, H+ transporting, lysosomal V1 subunit C2; ATPase, H+ transporting, V1 subunit C; ATPase, H+ transporting, V1 subunit C, isoform 2; OTTMUSP00000028152; V-ATPase subunit C 2; V-type proton ATPase subunit C 2; Vacuolar proton pump subunit C 2; VATC2
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Gene Symbols: Atp6v1c2
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Molecular weight:
48,350 Da
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Basal Isoelectric point:
6.31
Predict pI for various phosphorylation states
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