EFCAB6 Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex. Specifically expressed in the testis. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Chromosomal Location of mouse Ortholog: 15|15 E1-E2
Cellular Component:  nucleoplasm; nucleus
Molecular Function:  calcium ion binding; metal ion binding
Reference #:  Q6P1E8 (UniProtKB)
Alt. Names/Synonyms: 4931407K02Rik; 4932408N08Rik; bM150J22.2; bM150J22.2 (novel protein (4931407K02RIK, 4932408N08RIK)); DJ-1-binding protein; DJBP; EF-hand calcium binding domain 6; EF-hand calcium-binding domain-containing protein 6; Efcab6; EFCB6; Kiaa1672; mKIAA1672
Gene Symbols: Efcab6
Molecular weight: 175,771 Da
Basal Isoelectric point: 9.02  Predict pI for various phosphorylation states
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EFCAB6

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene  |  NURSA