EFCAB6 Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex. Specifically expressed in the testis. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 22q13.2-q13.31
Cellular Component:  nucleoplasm
Molecular Function:  calcium ion binding
Reference #:  Q5THR3 (UniProtKB)
Alt. Names/Synonyms: CAP-binding protein complex interacting protein 1; CAP-binding protein complex-interacting protein 1; DJ-1-binding protein; dJ185D5.1; DJBP; EF-hand calcium binding domain 6; EF-hand calcium-binding domain-containing protein 6; EFCAB6; EFCB6; epididymis secretory sperm binding protein; FLJ23588; HSCBCIP1; KIAA1672
Gene Symbols: EFCAB6
Molecular weight: 172,930 Da
Basal Isoelectric point: 8.67  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  NURSA  |  InnateDB  |  Ensembl Protein