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EFCAB6
Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex. Specifically expressed in the testis. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor |
| Chromosomal Location of human Ortholog: 22q13.2-q13.31 |
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Cellular Component:
cell projection; cytoplasm; cytoskeleton; nucleoplasm
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Molecular Function:
calcium ion binding
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Reference #:
Q5THR3
(UniProtKB)
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Alt. Names/Synonyms: CAP-binding protein complex interacting protein 1; CAP-binding protein complex-interacting protein 1; DJ-1-binding protein; dJ185D5.1; DJBP; EF-hand calcium binding domain 6; EF-hand calcium-binding domain-containing protein 6; EFCAB6; EFCB6; epididymis secretory sperm binding protein; FLJ23588; HSCBCIP1; KIAA1672
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Gene Symbols: EFCAB6
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Molecular weight:
172,930 Da
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Basal Isoelectric point:
8.67
Predict pI for various phosphorylation states
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