SENP5 Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division. Belongs to the peptidase C48 family. Note: This description may include information from UniProtKB.
Protein type: EC 3.4.22.68; Nucleolus; Protease
Chromosomal Location of Human Ortholog: 3q29
Cellular Component:  nucleolus; nucleoplasm
Molecular Function:  protein binding; ubiquitin-like protein-specific protease activity
Biological Process:  cell cycle; cell division; protein sumoylation
Reference #:  Q96HI0 (UniProtKB)
Alt. Names/Synonyms: DKFZp564O1016; FLJ42398; MGC27076; SENP5; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5; SUMO1/sentrin specific peptidase 5; SUMO1/sentrin specific protease 5
Gene Symbols: SENP5
Molecular weight: 86,693 Da
Basal Isoelectric point: 9.3  Predict pI for various phosphorylation states
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SENP5

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene