IARS2 Belongs to the class-I aminoacyl-tRNA synthetase family. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Aminoacyl-tRNA synthetase; EC; Ligase; Mitochondrial; Translation; Translation regulation
Chromosomal Location of Human Ortholog: 1|1 H5
Cellular Component:  cytosol; mitochondrion
Molecular Function:  aminoacyl-tRNA editing activity; aminoacyl-tRNA ligase activity; ATP binding; isoleucine-tRNA ligase activity; ligase activity; nucleotide binding; tRNA binding
Biological Process:  isoleucyl-tRNA aminoacylation; mitochondrial translation; translation; tRNA aminoacylation for protein translation
Reference #:  Q8BIJ6 (UniProtKB)
Alt. Names/Synonyms: 2010002H18Rik; C79125; Iars2; IleRS; Isoleucine--tRNA ligase; Isoleucine--tRNA ligase, mitochondrial; isoleucine-tRNA synthetase 2, mitochondrial; Isoleucyl-tRNA synthetase; Isoleucyl-tRNA synthetase, mitochondrial; MGC63429; OTTMUSP00000024472; SYIM
Gene Symbols: Iars2
Molecular weight: 112,804 Da
Basal Isoelectric point: 6.37  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene