HDDC3 ppGpp hydrolyzing enzyme involved in starvation response. Belongs to the MESH1 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC
Chromosomal Location of human Ortholog: 15q26.1
Cellular Component: 
Molecular Function:  guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity; metal ion binding; protein binding
Reference #:  Q8N4P3 (UniProtKB)
Alt. Names/Synonyms: (ppGpp)ase; Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1; HD domain containing 3; HD domain-containing protein 3; HDDC3; MESH1; Metazoan SpoT homolog 1; MGC45386; Penta-phosphate guanosine-3'-pyrophosphohydrolase
Gene Symbols: HDDC3
Molecular weight: 20,329 Da
Basal Isoelectric point: 6.25  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene