CDKN2AIP Regulates DNA damage response in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence. Belongs to the CARF family. Ubiquitously expressed. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 8|8 B1.1
Cellular Component:  granular component; nucleolus; nucleoplasm; nucleus
Molecular Function:  p53 binding; RNA binding
Biological Process:  cellular response to DNA damage stimulus; negative regulation of cell growth; positive regulation of cell growth; positive regulation of signal transduction; regulation of protein stability
Reference #:  Q8BI72 (UniProtKB)
Alt. Names/Synonyms: 4921511I16Rik; AW208986; Carf; CDKN2A interacting protein; CDKN2A-interacting protein; Cdkn2aip; collaborates/cooperates with ARF (alternate reading frame) protein; Collaborator of ARF
Gene Symbols: Cdkn2aip
Molecular weight: 59,745 Da
Basal Isoelectric point: 9.27  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene