CDKN2AIP Regulates DNA damage response in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence. Belongs to the CARF family. Ubiquitously expressed. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 4q35.1
Cellular Component:  granular component; nucleolus; nucleoplasm
Molecular Function:  p53 binding; protein binding; RNA binding
Biological Process:  cellular response to DNA damage stimulus; negative regulation of cell growth; positive regulation of cell growth; positive regulation of signal transduction; regulation of protein stability
Reference #:  Q9NXV6 (UniProtKB)
Alt. Names/Synonyms: CARF; CDKN2A interacting protein; CDKN2A-interacting protein; CDKN2AIP; collaborates/cooperates with ARF (alternate reading frame) protein; Collaborator of ARF; FLJ20036
Gene Symbols: CDKN2AIP
Molecular weight: 61,125 Da
Basal Isoelectric point: 9.13  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene