INT4 Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Belongs to the Integrator subunit 4 family. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Transcription initiation complex
Chromosomal Location of Human Ortholog: 11q14.1
Cellular Component:  integrator complex; nucleoplasm; nucleus
Molecular Function:  protein binding
Biological Process:  snRNA processing; snRNA transcription from RNA polymerase II promoter
Reference #:  Q96HW7 (UniProtKB)
Alt. Names/Synonyms: Int4; Integrator complex subunit 4; INTS4; MGC16733; MST093; MSTP093
Gene Symbols: INTS4
Molecular weight: 108,171 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
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INT4

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene