snRNP G Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. Belongs to the snRNP Sm proteins family. Note: This description may include information from UniProtKB.
Protein type: RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 2p13.3
Cellular Component:  catalytic step 2 spliceosome; cytosol; methylosome; nucleoplasm; nucleus; small nuclear ribonucleoprotein complex; SMN-Sm protein complex; spliceosomal complex; U1 snRNP; U12-type spliceosomal complex; U2-type catalytic step 2 spliceosome; U2-type precatalytic spliceosome; U4 snRNP; U4/U6 x U5 tri-snRNP complex; U7 snRNP
Molecular Function:  protein binding
Biological Process:  histone mRNA metabolic process; import into nucleus; mRNA splicing, via spliceosome; RNA splicing; spliceosomal complex assembly; spliceosomal snRNP assembly; termination of RNA polymerase II transcription
Reference #:  P62308 (UniProtKB)
Alt. Names/Synonyms: MGC117317; PBSCG; RUXG; Sm protein G; Sm-G; Small nuclear ribonucleoprotein G; small nuclear ribonucleoprotein polypeptide G; SmG; snRNP G; snRNP-G; SNRPG
Gene Symbols: SNRPG
Molecular weight: 8,496 Da
Basal Isoelectric point: 8.98  Predict pI for various phosphorylation states
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snRNP G

Protein Structure Not Found.


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