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NIP7
Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. Belongs to the NIP7 family. Expressed in hematopoietic stem/progenitor cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Nucleolus; RNA-binding |
| Chromosomal Location of human Ortholog: 16q22.1 |
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Cellular Component:
cytosol; nucleolus; nucleoplasm; preribosome, large subunit precursor
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Molecular Function:
protein binding
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Biological Process:
ribosomal large subunit biogenesis; ribosome assembly
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Reference #:
Q9Y221
(UniProtKB)
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Alt. Names/Synonyms: 60S ribosome subunit biogenesis protein NIP7 homolog; CGI-37; FLJ10296; HSPC031; KD93; NIP7; NIP7, nucleolar pre-rRNA processing protein; nuclear import 7; nuclear import 7 homolog; nuclear import 7 homolog (S. cerevisiae); nucleolar pre-rRNA processing protein NIP7
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Gene Symbols: NIP7
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Molecular weight:
20,463 Da
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Basal Isoelectric point:
8.66
Predict pI for various phosphorylation states
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