CLIPR-59 Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 7|7 B1
Cellular Component:  cytoplasm; early endosome membrane; Golgi apparatus; membrane; membrane raft; plasma membrane; recycling endosome membrane; trans-Golgi network; trans-Golgi network membrane
Molecular Function:  ganglioside binding; microtubule binding; protein binding
Biological Process:  chaperone-mediated protein transport; fat cell differentiation; membrane biogenesis; negative regulation of microtubule polymerization; peptidyl-L-cysteine S-palmitoylation; positive regulation of apoptotic process; positive regulation of endocytosis; positive regulation of glucose transmembrane transport; positive regulation of protein localization to plasma membrane; positive regulation of protein phosphorylation
Reference #:  B9EHT4 (UniProtKB)
Alt. Names/Synonyms: 1500005P14Rik; AI844915; CAP-GLY domain containing linker protein 3; CAP-Gly domain-containing linker protein 3; clip-170 related protein 59 kDa; CLIP-170-related 59 kDa protein; CLIP-170-related protein; Clip3; CLIPR-59; Clipr59; Cytoplasmic linker protein 170-related 59 kDa protein; OTTMUSP00000028972
Gene Symbols: Clip3
Molecular weight: 59,587 Da
Basal Isoelectric point: 8.17  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein