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CLIPR-59
Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of Human Ortholog: 7|7 B1 |
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Cellular Component:
cytoplasm; early endosome membrane; Golgi apparatus; membrane; membrane raft; plasma membrane; recycling endosome membrane; trans-Golgi network; trans-Golgi network membrane
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Molecular Function:
ganglioside binding; microtubule binding; protein binding
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Biological Process:
chaperone-mediated protein transport; fat cell differentiation; membrane biogenesis; negative regulation of microtubule polymerization; peptidyl-L-cysteine S-palmitoylation; positive regulation of apoptotic process; positive regulation of endocytosis; positive regulation of glucose transmembrane transport; positive regulation of protein localization to plasma membrane; positive regulation of protein phosphorylation
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Reference #:
B9EHT4
(UniProtKB)
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Alt. Names/Synonyms: 1500005P14Rik; AI844915; CAP-GLY domain containing linker protein 3; CAP-Gly domain-containing linker protein 3; clip-170 related protein 59 kDa; CLIP-170-related 59 kDa protein; CLIP-170-related protein; Clip3; CLIPR-59; Clipr59; Cytoplasmic linker protein 170-related 59 kDa protein; OTTMUSP00000028972
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Gene Symbols: Clip3
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Molecular weight:
59,587 Da
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Basal Isoelectric point:
8.17
Predict pI for various phosphorylation states
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