CLIPR-59 Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of human Ortholog: 19q13.12
Cellular Component:  cell cortex; cytosol; early endosome membrane; Golgi stack; membrane raft; microtubule plus-end; nucleus; plasma membrane; recycling endosome membrane; trans-Golgi network; trans-Golgi network membrane
Molecular Function:  ganglioside binding; microtubule binding; microtubule plus-end binding; protein binding
Biological Process:  cytoplasmic microtubule organization; fat cell differentiation; membrane biogenesis; negative regulation of microtubule polymerization; peptidyl-L-cysteine S-palmitoylation; positive regulation of apoptotic process; positive regulation of endocytosis; positive regulation of glucose transmembrane transport; positive regulation of protein localization to plasma membrane; positive regulation of protein phosphorylation; protein transport along microtubule
Reference #:  Q96DZ5 (UniProtKB)
Alt. Names/Synonyms: CAP-GLY domain containing linker protein 3; CAP-Gly domain-containing linker protein 3; CLIP-170-related 59 kDa protein; CLIP-170-related protein; CLIP3; CLIPR-59; CLIPR59; Cytoplasmic linker protein 170-related 59 kDa protein; DKFZp586N1922; FLJ33413; restin-like 1; RSNL1
Gene Symbols: CLIP3
Molecular weight: 59,560 Da
Basal Isoelectric point: 7.93  Predict pI for various phosphorylation states
Select Structure to View Below

CLIPR-59

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein