SPATA5 ATP-dependent chaperone which uses the energy provided by ATP hydrolysis to generate mechanical force to disassemble protein complexes. May be involved in morphological and functional mitochondrial transformations during spermatogenesis. Belongs to the AAA ATPase family. AFG2 subfamily. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Ubiquitin conjugating system
Chromosomal Location of mouse Ortholog: 3|3 B
Cellular Component:  cytoplasm; mitochondrion
Molecular Function:  ATP binding; ATPase activity; hydrolase activity; nucleotide binding
Biological Process:  brain development; cell differentiation; multicellular organism development; spermatogenesis
Reference #:  Q3UMC0 (UniProtKB)
Alt. Names/Synonyms: 2510048F20Rik; AFG2H; ATPase family protein 2 homolog; C78064; OTTMUSP00000007950; Spaf; SPAT5; Spata5; spermatogenesis associated 5; spermatogenesis associated factor; Spermatogenesis-associated factor protein; Spermatogenesis-associated protein 5
Gene Symbols: Spata5
Molecular weight: 97,256 Da
Basal Isoelectric point: 8.48  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene