S6 May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Belongs to the eukaryotic ribosomal protein eS6 family. Note: This description may include information from UniProtKB.
Protein type: Translation
Chromosomal Location of Human Ortholog: 9p22.1
Cellular Component:  cell body; cytoplasmic ribonucleoprotein granule; cytosol; cytosolic small ribosomal subunit; dendrite; endoplasmic reticulum; nucleolus; nucleoplasm; nucleus; perinuclear region of cytoplasm; polysome; ribonucleoprotein complex; small ribosomal subunit
Molecular Function:  protein binding; protein kinase binding; structural constituent of ribosome
Biological Process:  activation-induced cell death of T cells; erythrocyte development; G1/S transition of mitotic cell cycle; gastrulation; glucose homeostasis; mammalian oogenesis stage; mitotic cell cycle checkpoint; negative regulation of apoptotic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; placenta development; positive regulation of apoptotic process; ribosomal small subunit biogenesis; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; T cell differentiation in thymus; T cell proliferation involved in immune response; TOR signaling; translation; translational initiation; viral transcription
Reference #:  P62753 (UniProtKB)
Alt. Names/Synonyms: 40S ribosomal protein S6; Phosphoprotein NP33; ribosomal protein S6; RPS6; RS6; S6; Small ribosomal subunit protein eS6
Gene Symbols: RPS6
Molecular weight: 28,681 Da
Basal Isoelectric point: 10.85  Predict pI for various phosphorylation states
CST Pathways:  Growth And Differentiation Control by MAPKs  |  PI3K/Akt Signaling  |  Translation: eIF4E and p70S6K
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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S6

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene