GJB4 Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. Belongs to the connexin family. Beta-type (group I) subfamily. Note: This description may include information from UniProtKB.
Protein type: Channel, misc.; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 4 D2.2|4 61.51 cM
Cellular Component:  cell junction; connexin complex; gap junction; integral component of membrane; integral component of plasma membrane; membrane; nucleolus; nucleus; plasma membrane
Molecular Function:  gap junction channel activity; protein binding
Biological Process:  cell communication; cell-cell signaling; gap junction-mediated intercellular transport; olfactory behavior; sensory perception of smell
Reference #:  Q02738 (UniProtKB)
Alt. Names/Synonyms: Cnx30.3; connexin 30.3; connexin b; Connexin-30.3; Cx30.3; CXB4; Cxn-30.3; Cxnb; Gap junction beta-4 protein; gap junction membrane channel protein beta 4; gap junction protein, beta 4; Gjb-4; Gjb4; OTTMUSP00000009767
Gene Symbols: Gjb4
Molecular weight: 30,389 Da
Basal Isoelectric point: 9.07  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene