VANGL1 Belongs to the Vang family. According to PubMed:11956595, ubiquitously expressed. According to PubMed:12011995, expressed specifically in testis and ovary. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis
Chromosomal Location of human Ortholog: 1p13.1
Cellular Component:  lateral plasma membrane; plasma membrane
Molecular Function:  protein binding
Biological Process:  pigmentation; Wnt signaling pathway, planar cell polarity pathway
Disease: Neural Tube Defects; Sacral Defect With Anterior Meningocele
Reference #:  Q8TAA9 (UniProtKB)
Alt. Names/Synonyms: KAI1 C-terminal interacting tetraspanin; KITENIN; Loop-tail protein 2 homolog; LPP2; MGC5338; STB2; STBM2; Strabismus 2; Van Gogh-like protein 1; vang-like 1 (van gogh, Drosophila); Vang-like protein 1; VANG1; VANGL planar cell polarity protein 1; VANGL1
Gene Symbols: VANGL1
Molecular weight: 59,975 Da
Basal Isoelectric point: 8.94  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below

VANGL1

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein