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APBB2
May modulate the internalization of amyloid-beta precursor protein. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Apoptosis |
| Chromosomal Location of mouse Ortholog: 5|5 C3.1 |
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Cellular Component:
cytoplasm; early endosome; endoplasmic reticulum; endosome; Golgi apparatus; nucleus
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Molecular Function:
amyloid-beta binding; protein binding; transcription factor binding
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Biological Process:
axon guidance; extracellular matrix organization; maintenance of lens transparency; negative regulation of apoptotic process; negative regulation of cell cycle phase transition; negative regulation of transcription by RNA polymerase II; neuron migration; positive regulation of apoptotic process; positive regulation of transcription by RNA polymerase II; protein stabilization; regulation of DNA-templated transcription; smooth muscle contraction
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Reference #:
Q9DBR4
(UniProtKB)
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Alt. Names/Synonyms: 2310007D03Rik; amyloid beta (A4) precursor protein-binding, family B, member 2; Amyloid beta A4 precursor protein-binding family B member 2; Amyloid beta precursor protein binding family B member 2; Amyloid-beta A4 precursor protein-binding family B member 2; Apbb2; FE65L; FE65L1; Rirl1; TR2L; Zfra; zinc finger-like protein
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Gene Symbols: Apbb2
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Molecular weight:
83,201 Da
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Basal Isoelectric point:
5.79
Predict pI for various phosphorylation states
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