APBB2 May modulate the internalization of amyloid-beta precursor protein. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 5|5 C3.1
Cellular Component:  cytoplasm; nucleus
Molecular Function:  amyloid-beta binding; histone acetyltransferase binding; protein binding; transcription factor binding
Biological Process:  actin filament-based movement; axon guidance; cell cycle arrest; extracellular matrix organization; negative regulation of apoptotic process; negative regulation of cell growth; neuron migration; positive regulation of apoptotic process; protein stabilization; regulation of transcription, DNA-templated
Reference #:  Q9DBR4 (UniProtKB)
Alt. Names/Synonyms: 2310007D03Rik; amyloid beta (A4) precursor protein-binding, family B, member 2; Amyloid beta A4 precursor protein-binding family B member 2; Amyloid-beta A4 precursor protein-binding family B member 2; Apbb2; FE65L; FE65L1; Rirl1; TR2L; Zfra; zinc finger-like protein
Gene Symbols: Apbb2
Molecular weight: 83,201 Da
Basal Isoelectric point: 5.79  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene