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SOLO
May act as a guanine nucleotide exchange factor (GEF). Expressed at higher level in the central nervous system and skeletal muscle and greater abundance in fetal than adult brain (at protein level). 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: GEF; GEF, Rac/Rho |
| Chromosomal Location of mouse Ortholog: 14|14 C2 |
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Cellular Component:
cytoplasm; cytosol; plasma membrane
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Molecular Function:
guanyl-nucleotide exchange factor activity
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Reference #:
Q3UPH7
(UniProtKB)
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Alt. Names/Synonyms: ARH40; Arhgef40; E130112L23Rik; FLJ10357; Gm669; Protein SOLO; Rho guanine nucleotide exchange factor (GEF) 40; Rho guanine nucleotide exchange factor 40; RIKEN cDNA E130112L23 gene; Solo
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Gene Symbols: Arhgef40
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Molecular weight:
165,132 Da
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Basal Isoelectric point:
5.42
Predict pI for various phosphorylation states
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