NDUFA8 Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA8 subunit family. Note: This description may include information from UniProtKB.
Protein type: EC; EC; Energy Metabolism - oxidative phosphorylation; Mitochondrial; Oxidoreductase
Chromosomal Location of human Ortholog: 9q33.2
Cellular Component:  mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial respiratory chain complex I; mitochondrion
Molecular Function:  NADH dehydrogenase (ubiquinone) activity; protein binding; protein-containing complex binding
Biological Process:  aerobic respiration; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; proton motive force-driven mitochondrial ATP synthesis
Disease: Mitochondrial Complex I Deficiency, Nuclear Type 37
Reference #:  P51970 (UniProtKB)
Alt. Names/Synonyms: CI-19kD; CI-PGIV; Complex I-19kD; Complex I-PGIV; MGC793; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; NADH-ubiquinone oxidoreductase 19 kDa subunit; NADH:ubiquinone oxidoreductase PGIV subunit; NADH:ubiquinone oxidoreductase subunit A8; NDUA8; NDUFA8; PGIV
Gene Symbols: NDUFA8
Molecular weight: 20,105 Da
Basal Isoelectric point: 7.58  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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