RFC3 The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. Belongs to the activator 1 small subunits family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of mouse Ortholog: 5|5 G3
Cellular Component:  Ctf18 RFC-like complex; DNA replication factor C complex; nucleus
Molecular Function:  ATP-dependent activity, acting on DNA; DNA binding; DNA clamp loader activity; protein binding; single-stranded DNA helicase activity
Biological Process:  DNA repair; DNA replication; DNA-templated DNA replication; positive regulation of DNA-directed DNA polymerase activity
Reference #:  Q8R323 (UniProtKB)
Alt. Names/Synonyms: 2810416I22Rik; 38kD; 38kDa; A1 38 kDa subunit; Activator 1 38 kDa subunit; Activator 1 subunit 3; AU022547; Recc; Recc3; replication factor C (activator 1) 3; replication factor C 3; Replication factor C 38 kDa subunit; Replication factor C subunit 3; replication factor C, 38 kDa; RF-C 38 kDa subunit; Rfc3; RFC38
Gene Symbols: Rfc3
Molecular weight: 40,526 Da
Basal Isoelectric point: 8.7  Predict pI for various phosphorylation states
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RFC3

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein