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RFC3
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. Belongs to the activator 1 small subunits family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: DNA-binding |
| Chromosomal Location of mouse Ortholog: 5|5 G3 |
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Cellular Component:
Ctf18 RFC-like complex; DNA replication factor C complex; nucleus
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Molecular Function:
ATP-dependent activity, acting on DNA; DNA binding; DNA clamp loader activity; protein binding; single-stranded DNA helicase activity
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Biological Process:
DNA repair; DNA replication; DNA-templated DNA replication; positive regulation of DNA-directed DNA polymerase activity
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Reference #:
Q8R323
(UniProtKB)
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Alt. Names/Synonyms: 2810416I22Rik; 38kD; 38kDa; A1 38 kDa subunit; Activator 1 38 kDa subunit; Activator 1 subunit 3; AU022547; Recc; Recc3; replication factor C (activator 1) 3; replication factor C 3; Replication factor C 38 kDa subunit; Replication factor C subunit 3; replication factor C, 38 kDa; RF-C 38 kDa subunit; Rfc3; RFC38
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Gene Symbols: Rfc3
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Molecular weight:
40,526 Da
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Basal Isoelectric point:
8.7
Predict pI for various phosphorylation states
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