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LRP10
Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver. Belongs to the LDLR family. Expressed in blood leukocyte, lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, skeletal muscle and heart. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral; Receptor, misc. |
| Chromosomal Location of human Ortholog: 14q11.2 |
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Cellular Component:
clathrin-coated pit; plasma membrane
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Molecular Function:
low-density lipoprotein particle receptor activity; protein binding
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Biological Process:
endocytosis; inner ear development; lipid metabolic process; lipid transport
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Reference #:
Q7Z4F1
(UniProtKB)
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Alt. Names/Synonyms: DKFZp564C1940; LDL receptor related protein 10; low density lipoprotein receptor-related protein 10; Low-density lipoprotein receptor-related protein 10; LRP-10; LRP10; LRP9; MGC142274; MGC142276; MGC8675; MST087; MSTP087
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Gene Symbols: LRP10
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Molecular weight:
76,193 Da
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Basal Isoelectric point:
5.3
Predict pI for various phosphorylation states
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CST Pathways:
ESC Pluripotency and Differentiation
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Microtubule Dynamics
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mTOR Signaling
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Translation: eIF4E and p70S6K
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Wnt/ß-Catenin Signaling
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