CLPS Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. Belongs to the colipase family. Note: This description may include information from UniProtKB.
Protein type: Activator; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17|17 A3.3
Cellular Component:  extracellular region
Molecular Function:  enzyme activator activity
Biological Process:  digestion; lipid catabolic process; lipid metabolic process; positive regulation of catalytic activity; response to bacterium; response to food
Reference #:  Q9CQC2 (UniProtKB)
Alt. Names/Synonyms: 2200003J09Rik; Clps; COL; Colipase; colipase, pancreatic; OTTMUSP00000028866
Gene Symbols: Clps
Molecular weight: 12,445 Da
Basal Isoelectric point: 8.04  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein