VGLL4 May act as a specific coactivator for the mammalian TEFs. Belongs to the vestigial family. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Transcription, coactivator/corepressor
Chromosomal Location of human Ortholog: 3p25.3-p25.2
Cellular Component:  nucleus
Molecular Function:  protein binding; transcription coactivator binding
Biological Process:  negative regulation of cardiac muscle cell proliferation; negative regulation of cell growth; negative regulation of DNA-templated transcription; negative regulation of hippo signaling; negative regulation of Wnt signaling pathway; positive regulation of protein catabolic process
Reference #:  Q14135 (UniProtKB)
Alt. Names/Synonyms: KIAA0121; Transcription cofactor vestigial-like protein 4; vestigial like 4; vestigial like 4 (Drosophila); vestigial like family member 4; Vestigial-like 4; Vgl-4; VGLL4
Gene Symbols: VGLL4
Molecular weight: 30,930 Da
Basal Isoelectric point: 8.49  Predict pI for various phosphorylation states
Select Structure to View Below

VGLL4

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein