ZNF218 Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). Belongs to the teashirt C2H2-type zinc-finger protein family. Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor
Chromosomal Location of human Ortholog: 20q13.2
Cellular Component: 
Molecular Function:  DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; metal ion binding; protein binding
Biological Process:  multicellular organism development
Reference #:  Q9NRE2 (UniProtKB)
Alt. Names/Synonyms: C20orf17; cell growth-inhibiting protein 7; DKFZp686K2480; FLJ33887; Ovarian cancer-related protein 10-2; OVC10-2; serologically defined colon cancer antigen 33 like; teashirt family zinc finger 2; Teashirt homolog 2; teashirt zinc finger homeobox 2; TSH2; TSHZ2; ZABC2; Zinc finger protein 218; ZNF218
Gene Symbols: TSHZ2
Molecular weight: 115,005 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein