BICC1 Putative RNA-binding protein. Acts as a negative regulator of Wnt signaling. May be involved in regulating gene expression during embryonic development. Belongs to the BicC family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 10q21.1
Cellular Component:  cytoplasm
Biological Process:  determination of left/right symmetry; heart development; negative regulation of canonical Wnt signaling pathway
Disease: Renal Dysplasia, Cystic, Susceptibility To
Reference #:  Q9H694 (UniProtKB)
Alt. Names/Synonyms: Bic-C; bicaudal C homolog 1; bicaudal C homolog 1 (Drosophila); BICC; BicC family RNA binding protein 1; BICC1; CYSRD; DKFZp686I21119; FGFR2-BICC1 fusion kinase protein; Protein bicaudal C homolog 1
Gene Symbols: BICC1
Molecular weight: 104,844 Da
Basal Isoelectric point: 8.75  Predict pI for various phosphorylation states
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BICC1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene