K9
May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly. Belongs to the intermediate filament family. Expressed in the terminally differentiated epidermis of palms and soles. Note: This description may include information from UniProtKB.
|
Protein type: Cytoskeletal |
Chromosomal Location of human Ortholog: 17q21.2 |
Cellular Component:
cytoskeleton; cytosol; keratin filament
|
Molecular Function:
structural constituent of cytoskeleton
|
Biological Process:
epidermis development; epithelial cell differentiation; intermediate filament organization; skin development; spermatogenesis
|
Disease: Palmoplantar Keratoderma, Epidermolytic
|
Reference #:
P35527
(UniProtKB)
|
Alt. Names/Synonyms: CK-9; cytokeratin 9; Cytokeratin-9; EPPK; K1C9; K9; keratin 9; keratin 9, type I; Keratin, type I cytoskeletal 9; Keratin-9; KRT9; type I cytoskeletal 9
|
Gene Symbols: KRT9
|
Molecular weight:
62,064 Da
|
Basal Isoelectric point:
5.14
Predict pI for various phosphorylation states
|