DDHD1 Probable phospholipase that hydrolyzes phosphatidic acid. The different isoforms may change the substrate specificity. Belongs to the PA-PLA1 family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.1.-; Phospholipase
Chromosomal Location of Human Ortholog: 14q22.1
Cellular Component:  cytosol
Molecular Function:  metal ion binding; protein binding
Biological Process:  lipid catabolic process; phosphatidic acid biosynthetic process; positive regulation of mitochondrial fission
Disease: Spastic Paraplegia 28, Autosomal Recessive
Reference #:  Q8NEL9 (UniProtKB)
Alt. Names/Synonyms: DDHD domain containing 1; DDHD domain-containing protein 1; DDHD1; FLJ34209; FLJ42555; KIAA1705; PA-PLA1; Phosphatidic acid-preferring phospholipase A1 homolog; phosphatidic acid-preferring phospholipase A1-like protein; Phospholipase DDHD1
Gene Symbols: DDHD1
Molecular weight: 100,435 Da
Basal Isoelectric point: 5.42  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein