|
BOLA3
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins. Probably acts together with NFU1. Belongs to the BolA/IbaG family. Widely expressed. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: Unknown function |
| Chromosomal Location of human Ortholog: 2p13.1 |
|
Cellular Component:
cytosol; iron-sulfur cluster assembly complex; mitochondrial matrix; mitochondrion; nuclear body
|
|
Molecular Function:
protein binding
|
|
Biological Process:
cell redox homeostasis; iron-sulfur cluster assembly; protein maturation by [4Fe-4S] cluster transfer
|
|
Disease: Multiple Mitochondrial Dysfunctions Syndrome 2
|
|
Reference #:
Q53S33
(UniProtKB)
|
|
Alt. Names/Synonyms: bolA family member 3; bolA homolog 3; bolA homolog 3 (E. coli); bolA-like 3; BolA-like protein 3; BOLA3; MMDS2
|
|
Gene Symbols: BOLA3
|
|
Molecular weight:
12,114 Da
|
|
Basal Isoelectric point:
9.66
Predict pI for various phosphorylation states
|
