TAF7 Functions as a component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively). Belongs to the TAF7 family. Ubiquitous. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 18|18 B3
Cellular Component:  cytoplasm; Golgi apparatus; MLL1 complex; nucleoplasm; nucleus; transcription factor complex; transcription factor TFIID complex; transcription factor TFTC complex
Molecular Function:  histone acetyltransferase binding; P-TEFb complex binding; protein binding; protein heterodimerization activity; TFIIH-class transcription factor complex binding; thyroid hormone receptor binding; transcription coactivator activity; transcription factor binding; transcription regulatory region DNA binding; vitamin D receptor binding
Biological Process:  DNA-templated transcription, initiation; intracellular estrogen receptor signaling pathway; negative regulation of histone acetylation; negative regulation of protein kinase activity; negative regulation of transcription by RNA polymerase II; negative regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; RNA polymerase II preinitiation complex assembly; transcription by RNA polymerase II; transcription initiation from RNA polymerase II promoter
Reference #:  Q9R1C0 (UniProtKB)
Alt. Names/Synonyms: 55kD; 55kDa; AI607308; BB007175; RNA polymerase II TBP-associated factor subunit F; TAF(II)55; Taf2; Taf2f; Taf7; TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55 kDa; TAFI; TAFII-55; TAFII55; TATA box binding protein (TBP) associated factor, RNA polymerase II, F, 55 kDa; TATA-box binding protein associated factor 7; Transcription initiation factor TFIID 55 kDa subunit; Transcription initiation factor TFIID subunit 7
Gene Symbols: Taf7
Molecular weight: 39,126 Da
Basal Isoelectric point: 5.2  Predict pI for various phosphorylation states
CST Pathways:  Protein Acetylation
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene