SERPINB10
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus. Belongs to the serpin family. Ov-serpin subfamily. Expressed specifically in myeloid cells and the bone marrow. Note: This description may include information from UniProtKB.
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Protein type: Inhibitor |
Chromosomal Location of human Ortholog: 18q22.1 |
Cellular Component:
cytosol; extracellular space; ficolin-1-rich granule membrane; nucleoplasm; plasma membrane; secretory granule membrane
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Molecular Function:
serine-type endopeptidase inhibitor activity
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Biological Process:
negative regulation of endopeptidase activity
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Reference #:
P48595
(UniProtKB)
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Alt. Names/Synonyms: Bomapin; Peptidase inhibitor 10; PI-10; PI10; protease inhibitor 10 (ovalbumin type, bomapin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10; Serpin B10; serpin family B member 10; serpin peptidase inhibitor, clade B (ovalbumin), member 10; SERPINB10; SPB10
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Gene Symbols: SERPINB10
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Molecular weight:
45,403 Da
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Basal Isoelectric point:
5.8
Predict pI for various phosphorylation states
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