SLC44A1 Choline transporter. May be involved in membrane synthesis and myelin production. Belongs to the CTL (choline transporter-like) family. Expressed in various cells of the hematopoietic system. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of human Ortholog: 9q31.1-q31.2
Cellular Component:  cytosol; membrane; mitochondrial outer membrane; mitochondrion; nucleoplasm; plasma membrane
Molecular Function:  choline transmembrane transporter activity; transmembrane transporter activity
Biological Process:  choline catabolic process; choline transport; phosphatidylcholine biosynthetic process; transmembrane transport; transport across blood-brain barrier
Disease: Neurodegeneration, Childhood-onset, With Ataxia, Tremor, Optic Atrophy, And Cognitive Decline
Reference #:  Q8WWI5 (UniProtKB)
Alt. Names/Synonyms: CD92; CD92 protein; CDW92; CDW92 antigen; Choline transporter-like protein 1; CHTL1; CONATOC; CTL1; RP11-287A8.1; SLC44A1; solute carrier family 44 (choline transporter), member 1; Solute carrier family 44 member 1; solute carrier family 44, member 1
Gene Symbols: SLC44A1
Molecular weight: 73,302 Da
Basal Isoelectric point: 8.93  Predict pI for various phosphorylation states
Select Structure to View Below

SLC44A1

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene