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SPECC1L
Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration. Belongs to the cytospin-A family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cell cycle regulation |
| Chromosomal Location of human Ortholog: 22q11.23 |
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Cellular Component:
actin cytoskeleton; cytoplasm; filamentous actin; gap junction; microtubule organizing center; spindle
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Molecular Function:
protein binding
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Biological Process:
actin cytoskeleton organization; cell adhesion; cell cycle; cell division
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Disease: Facial Clefting, Oblique, 1; Hypertelorism, Teebi Type
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Reference #:
Q69YQ0
(UniProtKB)
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Alt. Names/Synonyms: cytokinesis and spindle organization A; cytospin A; Cytospin-A; CYTSA; GBBB2; KIAA0376; OBLFC1; Renal carcinoma antigen NY-REN-22; SPECC1-like protein; SPECC1L; sperm antigen with calponin homology and coiled-coil domains 1 like; sperm antigen with calponin homology and coiled-coil domains 1-like; TBHS
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Gene Symbols: SPECC1L
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Molecular weight:
124,544 Da
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Basal Isoelectric point:
5.55
Predict pI for various phosphorylation states
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