SPECC1L Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration. Belongs to the cytospin-A family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation
Chromosomal Location of human Ortholog: 22q11.23
Cellular Component:  actin cytoskeleton; cytosol; gap junction; spindle
Biological Process:  cell adhesion; cell cycle; cell division
Disease: Facial Clefting, Oblique, 1; Hypertelorism, Teebi Type; Opitz Gbbb Syndrome, Type Ii
Reference #:  Q69YQ0 (UniProtKB)
Alt. Names/Synonyms: cytokinesis and spindle organization A; cytospin A; Cytospin-A; CYTSA; GBBB2; KIAA0376; OBLFC1; Renal carcinoma antigen NY-REN-22; SPECC1-like protein; SPECC1L; sperm antigen with calponin homology and coiled-coil domains 1 like; sperm antigen with calponin homology and coiled-coil domains 1-like; TBHS
Gene Symbols: SPECC1L
Molecular weight: 124,602 Da
Basal Isoelectric point: 5.52  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene  |  InnateDB