Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway. Expressed in thymus, spleen, heart, testis, brain, placenta, muscle and pancreas. Isoform 1 is highly expressed in the small intestine, heart, testis, prostate, thymus, placenta and thyroid. Isoform 3 is highly expressed in stomach, uterus, placenta, trachea and thyroid. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Biological Process: B cell receptor signaling pathway; cell migration; cellular response to DNA damage stimulus; Fc-epsilon receptor signaling pathway; myotube cell development; negative regulation of transcription by RNA polymerase II; negative regulation of vascular smooth muscle cell differentiation; positive regulation of B cell proliferation; positive regulation of myoblast fusion; positive regulation of transcription, DNA-templated; regulation of regulatory T cell differentiation; regulation of transcription, DNA-templated; response to drug