IPPK
Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis. Belongs to the IPK1 type 2 family. Ubiquitously expressed, with high expression in heart, brain, testis and placenta. Note: This description may include information from UniProtKB.
Molecular Function: ATP binding; inositol pentakisphosphate 2-kinase activity; molecular adaptor activity; protein binding
Biological Process: inositol phosphate biosynthetic process; inositol phosphate metabolic process; phosphorylation; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I