MYO9A Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho activity in neurons, has a role in the regulation of neuronal morphology and function. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rac/Rho; Membrane protein, integral; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 15q23
Cellular Component:  axonal growth cone; cytosol; integral component of membrane; unconventional myosin complex
Molecular Function:  actin binding; ATP binding; GTPase activator activity; metal ion binding; motor activity; protein binding
Biological Process:  bioluminescence; cell junction assembly; establishment of epithelial cell apical/basal polarity; intracellular signal transduction; positive regulation of GTPase activity; regulation of neuron projection arborization; regulation of small GTPase mediated signal transduction; visual perception
Disease: Myasthenic Syndrome, Congenital, 24, Presynaptic
Reference #:  B2RTY4 (UniProtKB)
Alt. Names/Synonyms: FLJ11061; FLJ13244; MGC71859; MYO9A; MYO9A variant protein; myosin IXA; Myosin-IXa; MYR7; Unconventional myosin-9a; Unconventional myosin-IXa
Gene Symbols: MYO9A
Molecular weight: 292,706 Da
Basal Isoelectric point: 9.03  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein