SLC25A37 Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme. Belongs to the mitochondrial carrier family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial
Chromosomal Location of Human Ortholog: 8p21.2
Cellular Component:  integral component of membrane; mitochondrial inner membrane
Biological Process:  iron ion homeostasis
Reference #:  Q9NYZ2 (UniProtKB)
Alt. Names/Synonyms: HT015; MFRN; MFRN1; Mitochondrial iron transporter 1; Mitochondrial solute carrier protein; mitoferrin; Mitoferrin-1; MSC; MSCP; predicted protein of HQ2217; PRO1278; PRO1584; PRO2217; SLC25A37; Solute carrier family 25 member 37; solute carrier family 25, member 37
Gene Symbols: SLC25A37
Molecular weight: 37,323 Da
Basal Isoelectric point: 9.33  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB