CDH6 Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 5p13.3
Cellular Component:  integral component of membrane; plasma membrane
Biological Process:  adherens junction organization; cell adhesion; Notch signaling pathway
Reference #:  P55285 (UniProtKB)
Alt. Names/Synonyms: CAD6; CADH6; cadherin 6; cadherin 6, K-cadherin (fetal kidney); cadherin 6, type 2, K-cadherin (fetal kidney); cadherin, fetal kidney; Cadherin-6; CDH6; K-cadherin; KCAD; Kidney cadherin
Gene Symbols: CDH6
Molecular weight: 88,309 Da
Basal Isoelectric point: 4.77  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below

CDH6

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB