HAPLN2 Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid. Belongs to the HAPLN family. Expressed only in adult brain. Note: This description may include information from UniProtKB.
Protein type: Extracellular matrix; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3 F1|3 38.78 cM
Cellular Component:  extracellular matrix; extracellular region
Molecular Function:  hyaluronic acid binding
Biological Process:  cell adhesion; central nervous system development; establishment of blood-nerve barrier; extracellular matrix assembly; skeletal system development
Reference #:  Q9ESM3 (UniProtKB)
Alt. Names/Synonyms: 4930401E20Rik; Brain link protein 1; Bral1; Hapln2; HPLN2; Hyaluronan and proteoglycan link protein 2
Gene Symbols: Hapln2
Molecular weight: 37,925 Da
Basal Isoelectric point: 9.3  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene