HAPLN2 Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid. Belongs to the HAPLN family. Expressed only in adult brain. Note: This description may include information from UniProtKB.
Protein type: Extracellular matrix; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1q23.1
Cellular Component: 
Molecular Function:  hyaluronic acid binding
Biological Process:  cell adhesion; establishment of blood-nerve barrier; extracellular matrix assembly
Reference #:  Q9GZV7 (UniProtKB)
Alt. Names/Synonyms: Brain link protein 1; brain link protein-1; BRAL1; HAPLN2; HPLN2; Hyaluronan and proteoglycan link protein 2
Gene Symbols: HAPLN2
Molecular weight: 37,775 Da
Basal Isoelectric point: 9.12  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene