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ASB6
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the ankyrin SOCS box (ASB) family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Adaptor/scaffold |
| Chromosomal Location of human Ortholog: 9q34.11 |
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Cellular Component:
cytosol
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Molecular Function:
protein binding
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Biological Process:
intracellular signal transduction; protein ubiquitination
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Reference #:
Q9NWX5
(UniProtKB)
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Alt. Names/Synonyms: ankyrin repeat and SOCS box containing 6; Ankyrin repeat and SOCS box protein 6; ankyrin repeat and SOCS box-containing 6; ASB-6; ASB6; FLJ20548; MGC1024
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Gene Symbols: ASB6
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Molecular weight:
47,136 Da
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Basal Isoelectric point:
5.62
Predict pI for various phosphorylation states
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