CSTB This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Belongs to the cystatin family. Note: This description may include information from UniProtKB.
Protein type: Inhibitor
Chromosomal Location of human Ortholog: 21q22.3
Cellular Component:  cytoplasm; cytosol; extracellular region; extracellular space; ficolin-1-rich granule lumen; nucleolus; secretory granule lumen; tertiary granule lumen
Molecular Function:  cysteine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity; protease binding
Biological Process:  adult locomotory behavior; negative regulation of endopeptidase activity; negative regulation of peptidase activity; negative regulation of proteolysis; neutrophil degranulation
Disease: Myoclonic Epilepsy Of Unverricht And Lundborg
Reference #:  P04080 (UniProtKB)
Alt. Names/Synonyms: CPI-B; CST6; CSTB; cystatin B; cystatin B (stefin B); Cystatin-B; CYTB; epididymis secretory sperm binding protein; EPM1; EPM1A; Liver thiol proteinase inhibitor; PME; stefin B; Stefin-B; STFB; ULD
Gene Symbols: CSTB
Molecular weight: 11,140 Da
Basal Isoelectric point: 6.96  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB