Curated Information
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Home > Curated Information Page > Cst Curation Set #276
Goss V (2004) CST Curation Set: 276; Year: 2004; Biosample/Treatment: cell line, CLL23LB4/-; Disease: chronic lymphocytic leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y389-p - BDP1 (human)
Modsite: sAEEAPLysKVtPRA SwissProt Entrez-Gene
Orthologous residues
BDP1 (human): Y389‑p, BDP1 iso2 (human): Y282‑p, BDP1 (mouse): Y381‑p, BDP1 (rat): Y381‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y168-p - Cas-L (human)
Modsite: GHGyVyEyPSRyQKD SwissProt Entrez-Gene
Orthologous residues
Cas‑L (human): Y168‑p, Cas‑L iso3 (human): Y168‑p, Cas‑L (mouse): Y167‑p, Cas‑L (rat): H167‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y15-p - CDK1 (human)
Modsite: EkIGEGtyGVVykGR SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y15-p - CDK2 (human)
Modsite: EkIGEGtyGVVykAR SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): Y15‑p, CDK2 iso2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y15-p - CDK3 (human)
Modsite: EkIGEGtyGVVyKAK SwissProt Entrez-Gene
Orthologous residues
CDK3 (human): Y15‑p, CDK3 (mouse): Y15‑p, CDK3 (cow): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y108-p - CYFIP1 (human)
Modsite: QPNRVEIyEkTVEVL SwissProt Entrez-Gene
Orthologous residues
CYFIP1 (human): Y108‑p, CYFIP1 iso2 (human): , CYFIP1 (mouse): Y108‑p, CYFIP1 (rat): Y108‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y108-p - CYFIP2 (human)
Modsite: QPNRVEIyEkTVEVL SwissProt Entrez-Gene
Orthologous residues
CYFIP2 (human): Y108‑p, CYFIP2 iso2 (human): Y108‑p, CYFIP2 (mouse): Y108‑p, CYFIP2 (rat):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y449-p - DOK1 (human)
Modsite: KsHNsALysQVQKSG SwissProt Entrez-Gene
Orthologous residues
DOK1 (human): Y449‑p, DOK1 iso3 (human): Y310‑p, DOK1 (mouse): Y450‑p, DOK1 (rat): Y448‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y319-p - DYRK1A (human)
Modsite: CQLGQRIyQyIQsRF SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y319‑p, DYRK1A iso2 (human): Y310‑p, DYRK1A iso4 (human): Y319‑p, DYRK1A (mouse): Y319‑p, DYRK1A (rat): Y319‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y321-p - DYRK1A (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y319-p - DYRK1A iso4 (human)
Modsite: CQLGQRIyQyIQSRF SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y319‑p, DYRK1A iso2 (human): Y310‑p, DYRK1A iso4 (human): Y319‑p, DYRK1A (mouse): Y319‑p, DYRK1A (rat): Y319‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y321-p - DYRK1A iso4 (human)
Modsite: LGQRIyQyIQSRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y271-p - DYRK1B (human)
Modsite: CQLGQRIyQyIQsRF SwissProt Entrez-Gene
Orthologous residues
DYRK1B (human): Y271‑p, DYRK1B iso2 (human): Y271‑p, DYRK1B (mouse): Y271‑p, DYRK1B (rat): Y271‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y273-p - DYRK1B (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1B (human): Y273‑p, DYRK1B iso2 (human): Y273‑p, DYRK1B (mouse): Y273‑p, DYRK1B (rat): Y273‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y29-p - EEF1A1 (human)
Modsite: tttGHLIykCGGIDk SwissProt Entrez-Gene
Orthologous residues
EEF1A1 (human): Y29‑p, EEF1A1 (mouse): Y29‑p, EEF1A1 (rat): Y29‑p, EEF1A1 (rabbit): Y29‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y29-p - EEF1A2 (human)
Modsite: tttGHLIykCGGIDk SwissProt Entrez-Gene
Orthologous residues
EEF1A2 (human): Y29‑p, EEF1A2 (mouse): Y29‑p, EEF1A2 (rat): Y29‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y412-p - FGR (human)
Modsite: RLIKDDEyNPCQGSK SwissProt Entrez-Gene
Orthologous residues
FGR (human): Y412‑p, FGR (mouse): Y400‑p, FGR (rat): Y400‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y420-p - Fyn (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Fyn (human): Y420‑p, Fyn iso2 (human): Y417‑p, Fyn iso3 (human): Y365‑p, Fyn (mouse): Y420‑p, Fyn (rat): Y420‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y56-p - G3BP-1 (human)
Modsite: GkPADAVyGQkEIHR SwissProt Entrez-Gene
Orthologous residues
G3BP‑1 (human): Y56‑p, G3BP‑1 (mouse): Y56‑p, G3BP‑1 (rat): Y56‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y1105-p - GRF-1 (human)
Modsite: RNEEENIysVPHDst SwissProt Entrez-Gene
Orthologous residues
GRF‑1 (human): Y1105‑p, GRF‑1 (mouse): Y1105‑p, GRF‑1 (rat): Y1105‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y279-p - GSK3A (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y216-p - GSK3B (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y411-p - Hck (human)
Modsite: RVIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Hck (human): Y411‑p, Hck iso2 (human): Y390‑p, Hck iso3 (human): Y389‑p, Hck iso4 (human): Y410‑p, Hck (mouse): Y409‑p, Hck (rat): Y409‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y352-p - HIPK1 (human)
Modsite: SkAVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK1 (human): Y352‑p, HIPK1 iso2 (human): Y352‑p, HIPK1 iso4 (human): , HIPK1 (mouse): Y352‑p, HIPK1 (rat): Y352‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y361-p - HIPK2 (human)
Modsite: SkAVCstyLQsRYyR SwissProt Entrez-Gene
Orthologous residues
HIPK2 (human): Y361‑p, HIPK2 (mouse): Y361‑p, HIPK2 (rat): Y361‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y485-p - HSP90B (human)
Modsite: EtQksIyyItGEskE SwissProt Entrez-Gene
Orthologous residues
HSP90B (human): Y485‑p, HSP90B (mouse): Y485‑p, HSP90B (rat): Y485‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y394-p - Lck (human)
Modsite: RLIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Lck (human): Y394‑p, Lck iso3 (human): Y424‑p, Lck (mouse): Y394‑p, Lck (rat): Y394‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y397-p - LYN (human)
Modsite: RVIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
LYN (human): Y397‑p, LYN iso2 (human): Y376‑p, LYN (mouse): Y397‑p, LYN iso2 (mouse): Y376‑p, LYN (rat): Y397‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y467-p - PIK3R1 (human)
Modsite: SREyDRLyEEytRTS SwissProt Entrez-Gene
Orthologous residues
PIK3R1 (human): Y467‑p, PIK3R1 iso2 (human): Y197‑p, PIK3R1 iso4 (human): Y467‑p, PIK3R1 (mouse): Y467‑p, PIK3R1 (rat): Y467‑p, PIK3R1 (cow): Y467‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y413-p - SGK223 (human)
Modsite: ATQPEPIyAEsTKRK SwissProt Entrez-Gene
Orthologous residues
SGK223 (human): Y413‑p, SGK223 (mouse): Y391‑p, SGK223 (rat): Y391‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y419-p - Src (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Src (human): Y419‑p, Src iso2 (human): Y425‑p, Src (mouse): Y424‑p, Src iso2 (mouse): Y418‑p, Src (rat): Y419‑p, Src (chicken): Y416‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y705-p - STAT3 (human)
Modsite: DPGsAAPyLktKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human

Y426-p - Yes (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Yes (human): Y426‑p, Yes (mouse): Y424‑p, Yes (rat): Y424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic lymphocytic leukemia
Relevant cell lines - cell types - tissues:  CLL23LB4 (B lymphocyte)
Cellular systems studied:  cell lines
Species studied:  human