Goss V (2004) CST Curation Set: 256; Year: 2004; Biosample1/Treatment/Isotope: cell line, EOL-1/none/L, Biosample2/Treatment/Isotope: cell line, EOL-1/Gleevec/H; Disease: acute myelogenous leukemia; SILAC: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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Y15-p - CDK1 (human) ▲

Modsite: EkIGEGtyGVVykGR SwissProt Entrez-Gene Orthologous residues CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y15-p - CDK2 (human) ▲

Modsite: EkIGEGtyGVVykAR SwissProt Entrez-Gene Orthologous residues CDK2 (human): Y15‑p, CDK2 iso2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y15-p - CDK3 (human) ▲
Modsite: EkIGEGtyGVVyKAK SwissProt Entrez-Gene Orthologous residues CDK3 (human): Y15‑p, CDK3 (mouse): Y15‑p, CDK3 (cow): Y15‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y319-p - DYRK1A (human) ▲

Modsite: CQLGQRIyQyIQsRF SwissProt Entrez-Gene Orthologous residues DYRK1A (human): Y319‑p, DYRK1A iso2 (human): Y310‑p, DYRK1A iso4 (human): Y319‑p, DYRK1A (mouse): Y319‑p, DYRK1A (rat): Y319‑p, DYRK1A (rabbit): ‑ Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y321-p - DYRK1A (human) ▲

Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene Orthologous residues DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit): ‑ Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y319-p - DYRK1A iso4 (human) ▲

Modsite: CQLGQRIyQyIQSRF SwissProt Entrez-Gene Orthologous residues DYRK1A (human): Y319‑p, DYRK1A iso2 (human): Y310‑p, DYRK1A iso4 (human): Y319‑p, DYRK1A (mouse): Y319‑p, DYRK1A (rat): Y319‑p, DYRK1A (rabbit): ‑ Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y321-p - DYRK1A iso4 (human) ▲

Modsite: LGQRIyQyIQSRFYR SwissProt Entrez-Gene Orthologous residues DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit): ‑ Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y271-p - DYRK1B (human) ▲

Modsite: CQLGQRIyQyIQsRF SwissProt Entrez-Gene Orthologous residues DYRK1B (human): Y271‑p, DYRK1B iso2 (human): Y271‑p, DYRK1B (mouse): Y271‑p, DYRK1B (rat): Y271‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y273-p - DYRK1B (human) ▲

Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene Orthologous residues DYRK1B (human): Y273‑p, DYRK1B iso2 (human): Y273‑p, DYRK1B (mouse): Y273‑p, DYRK1B (rat): Y273‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y29-p - EEF1A1 (human) ▲

Modsite: tttGHLIykCGGIDk SwissProt Entrez-Gene Orthologous residues EEF1A1 (human): Y29‑p, EEF1A1 (mouse): Y29‑p, EEF1A1 (rat): Y29‑p, EEF1A1 (rabbit): Y29‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y29-p - EEF1A2 (human) ▲
Modsite: tttGHLIykCGGIDk SwissProt Entrez-Gene Orthologous residues EEF1A2 (human): Y29‑p, EEF1A2 (mouse): Y29‑p, EEF1A2 (rat): Y29‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y1105-p - GRF-1 (human) ▲

Modsite: RNEEENIysVPHDst SwissProt Entrez-Gene Orthologous residues GRF‑1 (human): Y1105‑p, GRF‑1 (mouse): Y1105‑p, GRF‑1 (rat): Y1105‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y279-p - GSK3A (human) ▲

Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene Orthologous residues GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y216-p - GSK3B (human) ▲

Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene Orthologous residues GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y762-p - PDGFRA (human) ▲

Modsite: sDIQRsLyDRPAsyK SwissProt Entrez-Gene Orthologous residues PDGFRA (human): Y762‑p, PDGFRA (mouse): Y762‑p, PDGFRA (rat): Y761‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y768-p - PDGFRA (human) ▲

Modsite: LyDRPAsyKKKSMLD SwissProt Entrez-Gene Orthologous residues PDGFRA (human): Y768‑p, PDGFRA (mouse): Y768‑p, PDGFRA (rat): Y767‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y849-p - PDGFRA (human) ▲

Modsite: DIMHDsNyVsKGSTF SwissProt Entrez-Gene Orthologous residues PDGFRA (human): Y849‑p, PDGFRA (mouse): Y849‑p, PDGFRA (rat): Y848‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y452-p - PIK3R1 (human) ▲

Modsite: VGKkLHEyNtQFQEk SwissProt Entrez-Gene Orthologous residues PIK3R1 (human): Y452‑p, PIK3R1 iso2 (human): Y182‑p, PIK3R1 iso4 (human): Y452‑p, PIK3R1 (mouse): Y452‑p, PIK3R1 (rat): Y452‑p, PIK3R1 (cow): Y452‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y453-p - PIK3R2 (human) ▲

Modsite: LkVyHQQyQDksREy SwissProt Entrez-Gene Orthologous residues PIK3R2 (human): Y453‑p, PIK3R2 (mouse): Y447‑p, PIK3R2 (rat): Y447‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y694-p - STAT5A (human) ▲

Modsite: LAkAVDGyVkPQIkQ SwissProt Entrez-Gene Orthologous residues STAT5A (human): Y694‑p, STAT5A (mouse): Y694‑p, STAT5A iso2 (mouse): ‑, STAT5A (rat): Y694‑p, STAT5A (fruit fly): ‑, STAT5A (sheep): Y694‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human

Y699-p - STAT5B (human) ▲

Modsite: tAkAVDGyVkPQIkQ SwissProt Entrez-Gene Orthologous residues STAT5B (human): Y699‑p, STAT5B (mouse): Y699‑p, STAT5B (rat): Y699‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  EOL-1 (myeloid) Cellular systems studied:  cell lines Species studied:  human