Curated Information
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Home > Curated Information Page > PubMed Id: 30320402
Zhao Y, et al. (2018) In vitro neutralization of autocrine IL‑10 affects Op18/stathmin signaling in non‑small cell lung cancer cells. Oncol Rep 30320402
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S16-p - STMN1 (human)
Modsite: kELEKrAsGQAFELI SwissProt Entrez-Gene
Orthologous residues
STMN1 (human): S16‑p, STMN1 iso2 (human): S16‑p, STMN1 (mouse): S16‑p, STMN1 (rat): S16‑p, STMN1 (chicken): S16‑p, STMN1 (cow): S16‑p

S25-p - STMN1 (human)
Modsite: QAFELILsPrskEsV SwissProt Entrez-Gene
Orthologous residues
STMN1 (human): S25‑p, STMN1 iso2 (human): S25‑p, STMN1 (mouse): S25‑p, STMN1 (rat): S25‑p, STMN1 (chicken): G25‑p, STMN1 (cow): S25‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H1299 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
antibody decrease

S38-p - STMN1 (human)
Modsite: sVPEFPLsPPkKkDL SwissProt Entrez-Gene
Orthologous residues
STMN1 (human): S38‑p, STMN1 iso2 (human): S38‑p, STMN1 (mouse): S38‑p, STMN1 (rat): S38‑p, STMN1 (chicken): S38‑p, STMN1 (cow): S38‑p

S63-p - STMN1 (human)
Modsite: AAEERRksHEAEVLk SwissProt Entrez-Gene
Orthologous residues
STMN1 (human): S63‑p, STMN1 iso2 (human): S63‑p, STMN1 (mouse): S63‑p, STMN1 (rat): S63‑p, STMN1 (chicken): S63‑p, STMN1 (cow): S63‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Disease tissue studied:  lung cancer, non-small cell lung cancer
Relevant cell lines - cell types - tissues:  NCI-H1299 (pulmonary)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
antibody decrease